Which type of pesticides is typically least toxic to humans and animals?

Biorational pesticides are designed to target specific pests while having minimal harmful effects on non-target organisms, including humans and animals. They often utilize naturally occurring substances or mimic natural biological processes, making them generally safer compared to synthetic or broad-spectrum pesticides. Biorational pesticides may include materials such as plant extracts, microbial agents, and pheromones, all of which tend to have lower toxicity profiles.

In contrast, synthetic pesticides are man-made chemicals that can be highly effective but also potentially toxic to a wide range of organisms, including humans, if not used correctly. Insecticides specifically target insects, but they can still pose risks to other beneficial organisms and mammals. Nematicides are designed to kill nematodes and can also be particularly toxic, especially to pets and other wildlife. Therefore, when considering toxicity to humans and animals, biorational pesticides stand out as the least toxic option.